If you're creating a Zend_DB object at the start you can create a query using that. Have a look at this entry in the manual : https://framework.zend.com/manual/1.12/en/zend.db.statement.html
$stmt = $db->query('SELECT * FROM bugs WHERE reported_by = ? AND bug_status = ?', array('goofy', 'FIXED') );
Or
$sql = 'SELECT * FROM bugs WHERE reported_by = ? AND bug_status = ?';$stmt = new Zend_Db_Statement_Mysqli($db, $sql);